/home/corante/public_html/pipeline/ en-us derek-lowe@sbcglobal.net 2007-12-12T08:22:34-05:00 hourly 1 2000-01-01T12:00+00:00 http://pipeline.corante.com/archives/2007/12/12/medchem_layoffs_on_the_front_page.php Yesterday’s Wall Street Journal ran a front-page article on the chemistry layoffs that have afflicted us in the drug industry. The piece (by Avery Johnson) focuses on a good example: Bob Sliskovic, the medicinal chemist who first synthesized Lipitor (as... 72934@/home/corante/public_html/pipeline/ Business and Markets 2007-12-12T08:22:34-05:00 http://pipeline.corante.com/archives/2007/06/06/massachusetts_moving.php And while I'm on the subject of that last post, I wanted to make a quick appeal to the readership. My new position will be taking me to the research-happy Greater Boston area, which I'm looking forward to. At the... 72372@/home/corante/public_html/pipeline/ Closing Time 2007-06-06T07:34:33-05:00 http://pipeline.corante.com/archives/2007/06/06/a_post_ive_been_looking_forward_to_for_months.php I'm very glad to announce that I've accepted an offer of a new research position. Thus ends a stretch of unemployment that began officially at the end of January, with warning having been served the previous November. That explains the... 72371@/home/corante/public_html/pipeline/ Closing Time 2007-06-06T06:00:03-05:00 http://pipeline.corante.com/archives/2007/04/12/layoffs_again.php I've heard from more than one source that Pfizer has laid off a large number of research staff this week in Groton. This seems to have taken people by surprise in many cases, since the expectation was just that everyone... 72209@/home/corante/public_html/pipeline/ Business and Markets 2007-04-12T08:07:03-05:00 http://pipeline.corante.com/archives/2007/03/11/more_help_wanted.php Back in November, I announced the impending closure of the Wonder Drug Factory, and there were plenty of people who responded with news of open positions. My colleagues and I really appreciated it - a number of interviews (and some... 72113@/home/corante/public_html/pipeline/ Closing Time 2007-03-11T15:23:02-05:00 http://pipeline.corante.com/archives/2007/02/28/have_we_got_a_job_for_you.php Since I'm still on the job-hunting trail, after the events described here, I think I'd find it a bit therapeutic to complain about one part of the process that's a complete waste of time. Now, there are open positions that... 72085@/home/corante/public_html/pipeline/ Closing Time 2007-02-28T20:49:43-05:00 http://pipeline.corante.com/archives/2007/02/05/a_break_whether_i_felt_like_it_or_not.php So begins my first week without employment since the late 1980s. And I'm not sure that that period counts, since it was just after my postdoc ended and I was looking for my first real job. I had a Humboldt... 71975@/home/corante/public_html/pipeline/ Closing Time 2007-02-05T20:43:28-05:00 http://pipeline.corante.com/archives/2007/01/29/open_for_business.php Tuesday is my last day at the Wonder Drug Factory. I've been hauling out boxes, emptying the freezer, signing forms, and shaking a lot of hands. I don't have anything lined up immediately, although I'm pursuing a couple of possibilities.... 71954@/home/corante/public_html/pipeline/ Closing Time 2007-01-29T21:19:41-05:00 http://pipeline.corante.com/archives/2007/01/12/ghost_town.php I'm nearly finished with two manuscripts to send out before departing the Wonder Drug Factory. One is the last paper from an earlier project - it's interesting stuff, but now I'm one of the last people on the author list... 71675@/home/corante/public_html/pipeline/ Closing Time 2007-01-12T08:37:15-05:00 http://pipeline.corante.com/archives/2007/01/02/out_with_the_old.php Now this is a new experience for me. Starting off the new year in the lab has usually been a time for me to clean up the office and bench and think about what I'm getting done (and how that... 71249@/home/corante/public_html/pipeline/ Closing Time 2007-01-02T09:21:30-05:00 http://pipeline.corante.com/archives/2006/12/28/cleans_down_to_what_should_be_the_shine.php One of the main things I'm going to have to do when I get back to my lab is clean it up. That's not something that I spend much time on, under ordinary conditions. For one thing, I don't run... 71100@/home/corante/public_html/pipeline/ Closing Time 2006-12-28T14:44:06-05:00 http://pipeline.corante.com/archives/2006/12/19/hi_my_name_is_.php I've had several inquiries about how the job hunt is going. Actually I'm not expecting a lot of news until well after the first of the year. Many of my lab associate colleagues are getting hired already, which is good... 70743@/home/corante/public_html/pipeline/ Closing Time 2006-12-19T10:02:36-05:00 http://pipeline.corante.com/archives/2006/11/21/the_paper_mountain.php Another thing a large research site has, and in mighty impressive quantities, is paper. Something's got to be done with it, but not all laboratory paper is created equal. Of course, a lot of the mass represents hard copies of... 69495@/home/corante/public_html/pipeline/ Closing Time 2006-11-21T09:59:13-05:00 http://pipeline.corante.com/archives/2006/11/21/the_paper_mountain.php Another thing a large research site has, and in mighty impressive quantities, is paper. Something's got to be done with it, but not all laboratory paper is created equal. Of course, a lot of the mass represents hard copies of... 69495@/home/corante/public_html/pipeline/ Closing Time 2006-11-21T09:59:13-05:00 http://pipeline.corante.com/archives/2006/11/15/vial_thirtythree_warp_drive.php As I mentioned the other day, I'm sprinting to finish some last experiments on my side project. These are all on the "vial thirty-three" system that I first described here and finally got to work reproducibly here. Looking back, I... 69198@/home/corante/public_html/pipeline/ Birth of an Idea 2006-11-15T20:49:25-05:00