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DBL%20Hendrix%20small.png College chemistry, 1983

Derek Lowe The 2002 Model

Dbl%20new%20portrait%20B%26W.png After 10 years of blogging. . .

Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: derekb.lowe@gmail.com Twitter: Dereklowe

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In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

In the Pipeline

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July 1, 2013

Travel and Upcoming Posts

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Posted by Derek

I'm traveling for the next couple of days, and then we have the July 4th holiday coming up. So blogging will be a bit irregular around here this week. By popular demand, I am planning a couple of large posts that follow up on the "Eight Toxic Foods" craziness, though. One will look at why some of the allowed US ingredients are banned in some other countries, and the other will look at the reverse: ingredients and additives that are banned in the US, but allowed abroad. Those will start showing up next week.

Comments (9) + TrackBacks (0) | Category: Blog Housekeeping


COMMENTS

1. BobChem on July 1, 2013 12:37 PM writes...

Did you see the Guardian story adding another six compounds to the ones listed by Buzzfeed? You are directly linked on that one. As a chemist I can appreciate that this article was written completely tongue-in-cheek. However, if you don't have a knowledge of what those "chemicals" really are than the article comes off as more scare-mongering than anything else. A link to the Wikipedia page for "irony" is not sufficient to let many of the readers of this article know that it is, in fact, ironic. I am torn, knowing that the article is a spoof, and knowing that it will be used as cannon-fodder.

Permalink to Comment

2. Project Osprey on July 2, 2013 6:29 AM writes...

In an attempt to get in on the whole issue of chemicals in our food – but before the signal to noise ratio goes through the roof again. I feel it should be pointed out that there are chemicals used in the production of most foods which have proven health consequences. There are 4 big ones that I’m thinking of, which between them are known to cause hyperactivity, heart disease, weight-gain, diabetes and a whole host of other conditions, including possible links to cancer. Their chemical structures are all very different but one in particular builds up in the body more than any other chemical I can think of. In extreme cases a lifetime of exposure can lead to levels so high that it literally smothers whole organs. The damaging effect of these chemicals is proven and in my part of the world the National Health Service spends billions annually dealing with the effects. So what are these killer compounds? Well in no particular order... Salt, fat, sugar, cholesterol.

All naturally occurring though.

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3. Uncle Sam on July 2, 2013 3:05 PM writes...

Derek, do you have any 4th of July recipes you care to share this year?

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4. Trent Nichols MD on July 2, 2013 4:38 PM writes...

I came across your October 19,2012 comment on a Google search linking LY2886721 and thioamide after Lilly in June announced it will pull the drug (BACE inhibitor) for Alzheimer's due to hepatotoxicity. It's been years since my BS in chemistry (65) but as a neurogastroenterologist and hepatologist and after 41 clinical phase 2-4 pharmaceutical trials, I have some idea of drug toxicity.

I will send you as an attachment a comment to www.Alzforum.org on the topic. I think it's relevant to your Oct 19, 2012 posting.

Trent Nichols MD

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5. DannoH on July 2, 2013 4:55 PM writes...

Response to #2 and #3 above: Candied Bacon recipe.

Lay out strips of thick cut smoked bacon on a cookie sheet, place on aluminum foil if you want to control the mess. Apply a smattering of fresh ground black pepper, then spoon and spread around brown sugar to lightly coat the bacon.

Place the assembled bacon on pan into the oven, and turn the oven to 325 degrees. Do not preheat the oven. Let the bacon cook for 30 - 40 minutes, then remove once the desired level of crispyness is achieved. Drain on paper towels, sugar side up, and enjoy as is, or shred and make into candied bacon snickerdoodle cookies.

Salt, Fat, Sugar and Cholesterol, all in one recipe! Happy holidays to those so celebrating.

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6. uncle sam on July 3, 2013 1:58 AM writes...

A different, non-chemjobber blog Uncle Sam!? Well, I should have guessed that nick was not that unique. At least his is with capital letters.

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7. anon on July 3, 2013 1:21 PM writes...

there can be only one uncle sam

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8. uncle sam on July 3, 2013 2:07 PM writes...

@7 - well, thank you, anon. I'll take that as a compliment. and likewise, I'm sure.

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9. uncle sam on July 3, 2013 3:47 PM writes...

#8 Impostor! Dammit, I knew it was a bad nickname after I came up with it to piss of 'uncle al'. He doesn't even post on chemjobber.

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