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October 24, 2012
Too Many Med Chem Journals?
The recent discussions on awful molecules in the med-chem literature got me to thinking the other day. There are many more med-chem journals now than there used to be. Back in the day, you had the Journal of Medicinal Chemistry, and that was that. Then in the early 1990s came Bioorganic and Medicinal Chemistry and Bioorganic and Medicinal Chemistry Letters. Now we've got ACS Medicinal Chemistry Letters and MedChemComm and ChemMedChem, among others. (And as we were seeing the other day, there are levels and levels as you move down, ranging from obscure-but-respectable, to just plain obscure, all the way to disreputable crap).
This at a time when industrial medicinal chemistry has been getting cut back. Now, on the other side of the ledger, you have all the folks who are cleaning out the file cabinets for publishable material to have on their C.V.s (and don't think that's not a real force). But in general, I have to wonder if the amount of medicinal chemistry being published from industry hasn't been going down.
Here, then is the question: is there enough decent medicinal chemistry being done to usefully fill all the pages of all these journals? My answer, as you might guess, is "Probably not". But I'd welcome other opinions.
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