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March 18, 2010
Make Your Compound Go Away
I'm not sure that the term will catch on, but this new paper proposes "antedrug" to describe a compound that's deliberately designed to be cleaved quickly to something inactive. I see where they're coming from - reverse of "prodrug" - but in spoken English it's too close to "anti-drug". Hasn't someone come up with this concept before? Perhaps they didn't bother to name it. . .
UpdateSomeone at AZ sends along this earlier reference to "antedrug".
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