Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases.
To contact Derek email him directly: email@example.com
I'm not sure that the term will catch on, but this new paper proposes "antedrug" to describe a compound that's deliberately designed to be cleaved quickly to something inactive. I see where they're coming from - reverse of "prodrug" - but in spoken English it's too close to "anti-drug". Hasn't someone come up with this concept before? Perhaps they didn't bother to name it. . .