Corante

About this Author
Derek Lowe
Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: derekb.lowe@gmail.com Twitter: Dereklowe

Chemistry and Drug Data: Drugbank
Emolecules
ChemSpider
Chempedia Lab
Synthetic Pages
Organic Chemistry Portal
PubChem
Not Voodoo
DailyMed
Druglib
Clinicaltrials.gov

Chemistry and Pharma Blogs:
Org Prep Daily
The Haystack
MedChem Buzz
Kilomentor
On Pharma
A New Merck, Reviewed
Liberal Arts Chemistry
One in Ten Thousand
Electron Pusher
Periodic Tabloid
All Things Metathesis
C&E News Blog
Propter Doc
Chemiotics II
The Chemical Notebook
Chemical Space
Noel O'Blog
In Vivo Blog
Terra Sigilatta
Chirality
BBSRC/Douglas Kell
ChemBark
Drug Discovery Opinion
Realizations in Biostatistics
Chemjobber
Pharmalot
WSJ Health Blog
ChemSpider Blog
Pharmagossip
Med-Chemist
Organic Chem - Education & Industry
Useful Chemistry
Chiral Jones
Pharma Strategy Blog
No Name No Slogan
Practical Fragments
SimBioSys
The Curious Wavefunction
Natural Product Man
Totally Synthetic
Fragment Literature
The F- Blog
Chemistry World Blog
Synthetic Nature
Chemistry Blog
Synthesizing Ideas
Carbon-Based Curiosities
Experimental Error
Business|Bytes|Genes|Molecules
Eye on FDA
Sigma-Aldrich ChemBlogs
Chemical Forums
Depth-First
Symyx Blog
P212121
ChemCafe
Sceptical Chymist
Lamentations on Chemistry
Computational Organic Chemistry
Mining Drugs
Henry Rzepa


Science Blogs and News:
Bad Science
The Loom
Uncertain Principles
Fierce Biotech
Blogs for Industry
Omics! Omics!
Young Female Scientist
Notional Slurry
Nobel Intent
SciTech Daily
Science Blog
FuturePundit
Aetiology
Gene Expression (I)
Gene Expression (II)
Sciencebase
Pharyngula
Adventures in Ethics and Science
Transterrestrial Musings
Slashdot Science
A Scientist's Life
Speculist
Cosmic Variance
The Capsule
Zeroth Order Approximation
Biology News Net


Medical Blogs
Med Tech Sentinel
DB's Medical Rants
Science-Based Medicine
GruntDoc
The Health Care Blog
Respectful Insolence
Black Triangle
Diabetes Mine


Economics and Business
Marginal Revolution
Arnold Kling
The Volokh Conspiracy
Knowledge Problem
The Stalwart


Politics / Current Events
Virginia Postrel
Tinkerty Tonk
Instapundit
Megan McArdle
Mickey Kaus
Colby Cosh
Alien Corn
No Watermelons


Belles Lettres
Two Blowhards
Critical Mass
Arts and Letters Daily
God of the Machine
Armavirumque
About Last Night
In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

In the Pipeline

« Theft at Eli Lilly | Main | More Blogroll »

March 17, 2010

Dietary Supplements, Charted

Email This Entry

Posted by Derek

I'm a complete sucker for dense but well-presented information, and this one isn't bad at all: here's a chart of nutritional supplements by the strength of the evidence for them in human trials. I haven't cross-checked the data, but the authors appear to have done some homework in PubMed, at least, and haven't included any non-human or in vitro data. The interactive version at the link is particularly fun to mess around with. (Thanks to a reader and commenter here who put me on to this).

Comments (9) + TrackBacks (0) | Category: Snake Oil


COMMENTS

1. Skeptic on March 17, 2010 3:04 PM writes...

International Research = Google Ranking + # of Statistical Mumbo Jumbo studies from "Scientists"

Now thats Snake Oil!

Permalink to Comment

2. Sili on March 17, 2010 3:40 PM writes...

Ben Goldacre loves that site, but he hasn't pimped that particular graphic yet.

You've seen the climate one of course.

Permalink to Comment

3. Anonymous on March 17, 2010 4:18 PM writes...

I'm glad to have learnt what's good for my cholesterol, but what I'd really like to know is why my doctor believes that with cholesterol "the lower, the better". That seems rather implausible somehow.

Permalink to Comment

4. Cloud on March 17, 2010 6:07 PM writes...

My software engineer husband loves that site, too.

There's a really recent paper out with a possible mechanism for why vitamin D improves immune function. I actually wrote it up a couple days ago on my blog... we've been taking vitamin D for awhile, because any family with kids in day care is all about improving immune function.

Permalink to Comment

5. Anonymous BMS Researcher on March 17, 2010 8:21 PM writes...

I like the fact that they make full details complete with citations to sources, available as a Google Docs spreadsheet, and encourage readers to send them citations of evidence they might have missed.

I have felt for many years that many supplement makers like to make drug-like-claims without having to generate the sort of evidence we must generate before regulators will approve the claims we make about our products. Yes, the fine print says "these claims aren't FDA-approved," but I suspect most of their customers believe the claims anyway given their anti-science and anti-big-pharma worldview.

Permalink to Comment

6. cliffintokyo on March 18, 2010 4:05 AM writes...

Really interesting, and nice original visuals.
Would not have found this without your signpost.
Thanks!

Permalink to Comment

7. Vader on March 18, 2010 9:24 AM writes...

The relatively high rankings for st. john's wort for depression and cinnamon for diabetes are a blow to its credibility, at least with me.

Permalink to Comment

8. thomas on March 18, 2010 11:20 AM writes...

It's a pity they don't distinguish between "no evidence as to whether this works" and "good evidence that this doesn't work for the particular indications it claims".

For example, there's good large-scale randomized-trial evidence that beta-carotene supplementation doesn't do any good, and reasonable evidence that gingko doesn't prevent dementia. Turmeric, on the other hand, is in the 'no (human) evidence' category.

Permalink to Comment

9. Skeptic on March 18, 2010 11:46 PM writes...

"The detection of *OH production in cells is therefore extremely difficult (if not impossible) ..."

Free-Radical-Induced DNA Damage and its Repair
von Sonntag
Springer, 2006

But that doesn't stop the consumer from spending bucks on useless antioxidants in an attempt at attenuating the free radicals. Why bother spending all that money on R&D when all you need to move product is a quack on the tube and the so-called science journals playing the role of rating agencies. Antioxidants: Rated Triple AAA endorsed by Dr. Schnoz...buying frenzy commences


Permalink to Comment

POST A COMMENT




Remember Me?



EMAIL THIS ENTRY TO A FRIEND

Email this entry to:

Your email address:

Message (optional):




RELATED ENTRIES
Academia and Industry, Suing Each Other
Let's Start Off the Meeting With An Ad, OK?
The Academic-Industrial Collaboration in Drug Discovery Panel: Today
Glass Structure, Atom by Atom
How the Andrulis Paper Got Published
AstraZeneca in Waltham
Fluorine NMR: Why Not?
AstraZeneca Layoffs and Closings