Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases.
To contact Derek email him directly: derekb.lowe@gmail.com
Twitter: Dereklowe
This isn't exactly med-chem, but its focus probably overlaps with the interests of a number of readers around here. I recently came across a copy of A Field Guide to Bacteria and enjoyed it very much. I don't think there's another book quite like it available: it describes where you're likely to find different varieties of bacteria (from hot springs to your fridge), how they behave in a natural environment (as opposed to a culture dish) and how to identify them by field marks, if possible. It's not written for microbiologists, but it can provide a different perspective even if you work in the field (since many people that do focus on pathogens - really a very small subset of bacteria, when you get down to it).
I'm already inspired to set up some Winogradsky columns with my kids, perhaps with some unusual chemical additives to see what happens. If we discover anything, I'll report back. . .
Hi Derek, new reader here. Thanks for the recommendation! I'm a microbial ecologist, so I'm always pleased when something enters the public sphere about microbes that aren't OMG TEH GERMS.
3. Curt Fischer on February 26, 2010 2:55 PM writes...
Recommendation seconded! I thought I was the only one who loved this thing. If you do Winogradsky columns, you should definitely try the trick with the magnets to isolate magnetotactic bacteria. So cool!
4. gillespie on February 26, 2010 3:01 PM writes...
I'd be careful with the Winogradsky column... you can grow some nasty things that will be more than happy to colonize your body in various invasive ways.
Bought that one a while back. I still have an empty olive jar sitting around somewhere that I mean to turn into a Winogradsky column one of these days.
My son and I setup a winogradsky column almost two years ago. We didn't seal it tightly so the sulfur smell drove it outside. I think most of the sulfur's gone as the reds have been replaced with greens. I wonder what'd happen if we dropped an egg on top....
If it is still in print, then you should read John Postgate's "Microbes and Man". I had the privilege of being John's first graduate student to finish their doctorate, many, many years ago in another life. Nice to see microbes attaining their correct place in life. Dave_n
1. Steve on February 26, 2010 12:19 PM writes...
Hi Derek, new reader here. Thanks for the recommendation! I'm a microbial ecologist, so I'm always pleased when something enters the public sphere about microbes that aren't OMG TEH GERMS.
Permalink to Comment2. Jordan on February 26, 2010 12:57 PM writes...
Neat idea for a book. Thanks for passing the recommendation along, Derek.
Permalink to Comment3. Curt Fischer on February 26, 2010 2:55 PM writes...
Recommendation seconded! I thought I was the only one who loved this thing. If you do Winogradsky columns, you should definitely try the trick with the magnets to isolate magnetotactic bacteria. So cool!
Permalink to Comment4. gillespie on February 26, 2010 3:01 PM writes...
I'd be careful with the Winogradsky column... you can grow some nasty things that will be more than happy to colonize your body in various invasive ways.
Permalink to Comment5. milkshake on February 26, 2010 4:01 PM writes...
I would prefer my kids playing with Clostridum and Vibrio cholerae - instead of making acetonperoxide.
Permalink to Comment6. Derek Lowe on February 26, 2010 4:16 PM writes...
Gillespie, I plan on keeping that sucker sealed up. If I do reach in to take a microscope sample, though, I'll glove up, etc.
Permalink to Comment7. Stephanie Jewett, RN, MBA on February 26, 2010 11:27 PM writes...
Interesting - I'll definitely pick up the book. Probably rather spooky as well! Stephanie
Permalink to Comment8. Epicanis on February 26, 2010 11:28 PM writes...
I happen to have a copy of that book right next to me at the moment, in a stack of other microbiology-nerd books. Definitely recommended.
Permalink to Comment9. Vader on February 28, 2010 5:41 PM writes...
Bought that one a while back. I still have an empty olive jar sitting around somewhere that I mean to turn into a Winogradsky column one of these days.
Permalink to Comment10. isaac on March 1, 2010 8:08 PM writes...
My son and I setup a winogradsky column almost two years ago. We didn't seal it tightly so the sulfur smell drove it outside. I think most of the sulfur's gone as the reds have been replaced with greens. I wonder what'd happen if we dropped an egg on top....
Permalink to Comment11. Dave_n on March 12, 2010 2:08 PM writes...
If it is still in print, then you should read John Postgate's "Microbes and Man". I had the privilege of being John's first graduate student to finish their doctorate, many, many years ago in another life. Nice to see microbes attaining their correct place in life. Dave_n
Permalink to Comment