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DBL%20Hendrix%20small.png College chemistry, 1983

Derek Lowe The 2002 Model

Dbl%20new%20portrait%20B%26W.png After 10 years of blogging. . .

Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: Twitter: Dereklowe

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December 24, 2009

Holiday Time Off

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Posted by Derek

Well, with the holidays and all, I'll be taking blog-time off until Monday. The pace of scientific discovery has slowed noticeably around here in the last few days (and from the traffic stats, I can tell it's slowing in lots of other places, too!) As usual, I've made notes about what I'm up to in the lab, so I can pick up the threads in January. I also have an interesting manuscript that I'm submitting for publication, which I hope to talk about here soon. I'd like to wish all my readers who are celebrating a Merry Christmas!

Comments (18) + TrackBacks (0) | Category: Blog Housekeeping


1. Santa on December 24, 2009 3:51 PM writes...

Wonder how many people out there have run a reaction on Christmas day?

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2. chiraljones on December 25, 2009 3:30 AM writes...

don't joke. my PI has said that when he was in grad-school, he was in lab on Christmas day. He didn't say this like he expected the rest of us to do the same, but he did say it with conviction that made it sound like it was no big deal and totally a normal occurrence.

scary stuff...

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3. MattW on December 25, 2009 8:55 AM writes...

Sadly, I have and really, just for fun, I might today, just-kidding

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4. Skinny on December 25, 2009 5:21 PM writes...

My daughter is running her first reaction on her new chemistry set today. May the circle be unbroken.

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5. Bored on December 26, 2009 10:21 PM writes...

RE #5 Zidane

Wow! Either those automated blog droids are at it again, or someone O.D.'d on ham or turkey over the holidays...

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6. RB Woodweird on December 27, 2009 10:31 PM writes...

I used to love working in the lab on Christmas Day. I figured it was one of the few days every other organic chemist in the world wasn't getting ahead of me.

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7. partial agonist on December 28, 2009 2:00 PM writes...

One Christmas I was near the end of my graduate work and had a list of compounds for which I thought it would certainly be nice to get C-13 NMR spectra.

It was hard to get adequate NMR time to do more than one c-13 a day, however, since most compounds were intermediates in a total systhesis and I had kept mg or submilligram quantities.

That Christmas day, though, I had full use of a Bruker 500 for just about all day! I must have gotten 12 or more samples analyzed.

Now the wife (finance at the time) was not particularly pleased, but the end was in sight and job interviews were in the future, so she dealt with it.

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8. riron2 on December 28, 2009 3:02 PM writes...

True story...Christmas day, professor calls Chinese-American grad student at home...

"I expect you to work today since your religion doesn't observe Christmas"

Grad student grudgingly shows up in the lab...

I don't miss those days at all!

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9. anon on December 28, 2009 8:41 PM writes...

Did it many times long ago on the holidays it was a quick work up maybe a column and set a new reaction ... a couple hours of work "usually"

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10. SynChem on December 29, 2009 1:54 PM writes...

I believe that the fact that there is less people in the labs this time of year can be bad for those deciding to go ahead and work in lab anyways. Lets not forget that it was about this time of year last year when that UCLA incident happened with the t-BuLi, resulting in the death of a lab tech. Perhaps if there would have been better first response from more qualified lab co-workers there may have been a better outcome.

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11. Chemjobber on December 29, 2009 3:23 PM writes...

It was actually today, December 29, that it happened last year. RIP Sheri Sangji.

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12. santa helper on December 30, 2009 10:12 AM writes...

Christmas gift from baran lab: palau'amine is done.

cant remember any other synthesis with >60 studies towards papers and theses.

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13. Jose on December 30, 2009 11:29 AM writes...

Baran is THE Man. Where does that tidbit come from??

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15. Bored on December 30, 2009 9:17 PM writes...


The droids are out in force on your blog in your absence. #15 Henry is a droid on pain meds to boot. Funny.

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16. Martyn on December 31, 2009 7:39 AM writes...

Surely it can't be hard to just block any comments containing 'findrxonline'? It's hardly going to come up in legitimate discussion very often, is it?

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17. Jose on January 1, 2010 9:31 PM writes...

Is the manuscript related to the Vial 33 experiments??

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18. Anonymous on January 4, 2010 1:27 PM writes...

"My daughter is running her first reaction on her new chemistry set today. May the circle be unbroken."

I got my son an old Champions manual. He appears to be delighted.

The circle is now complete.

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