1. Daniel Newby on July 1, 2008 1:20 PM writes...

If this comment appears, then the fix works.

2. Anonymous BMS Researcher on July 2, 2008 6:54 AM writes...

In Firefox 2.0.0.15 it's Tools/Options/Show Cookies

In MSIE it is more complicated. Here are the directions from its help pages:

To delete a single cookie

In Internet Explorer, click the Tools button, and then click Internet Options.
On the General tab, under Browsing history, click Settings.
Click the View files button.
Click the Name column heading to sort all the files alphabetically, and then scroll down until you see files that begin with the prefix Cookie:. All cookies will have that prefix, and they usually contain the name of the website that created the cookie.
Right-click the cookie you want to delete, click Delete, and then click Yes.
Close the window that contains the list of files, and then click OK twice to return to Internet Explorer.

3. Ger on July 2, 2008 7:01 AM writes...

Derek, would like to hear your comments and other readers, on the story by Ed Silverman of Pharmalot and the comments by readers, on Dr. Edward Tobinick (Dermatologist) and his alzheimer's claims and other practices.

http://www.pharmalot.com/2008/07/enbrel-alzheimers-and-a-controversial-doctor/
Enbrel, Alzheimer’s And A Controversial Doctor

4. Anonymous Big Pharma Researcher on July 2, 2008 7:58 AM writes...

3. Ger on July 2, 2008 7:01 AM wrote:...

> Derek, would like to hear your comments and other
> readers... on Dr. Edward Tobinick (Dermatologist)
> and his alzheimer's claims and other practices.

I don't work on AD, though I know a number of people who do. I can say this much: the pharmalot piece seems on its face to be reasonably well balanced. My gut feeling is, this bears many earmarks of pathological science -- but even if the odds on there being something to this are 100 to one against (which is how I would bet) -- the cost of testing it seems very small compared to the potential benefits. Therefore, either the folks at Amgen are idiots or they have information I don't have showing the idea is not worth pursuing.

On the pharmalot blog a number of people with strong views in favor of Dr. T's work are harshly critical of those who point out anecdotal evidence is bad science. The history of medicine is FULL of treatments, eventually proven worthless or even harmful, that everybody once thought to be valuable based on anecdotal evidence. Anybody who has been in pharma research for very long has seen many a cherished hypothesis that seemed plausible on mechanistic grounds and was supported by early results go down in flames once it was given a proper trial.

5. Hap on July 2, 2008 11:49 AM writes...

Um, the words "single-patient trial" do not inspire confidence in the work.

6. Hap on July 3, 2008 3:34 PM writes...

Anon. BMS. R.,

The IE version of the fix seems to work. Thank you.

7. Ian Musgrave on July 3, 2008 10:18 PM writes...

The fix in Firefox works.

8. Felicia on September 25, 2008 6:37 PM writes...

To: 4. Anonymous Big Pharma Researcher:

I would like to comment about the Pharmalot Blog. I am one of the ones posting that the treatment works, since it has helped my Mom. If you read the posts again, you will see that we are not saying that Anecdotal Evident AGAINST the treatment is bad science, we're saying that we have anectdotal evidence that it does work, and nobody's listening. Also, there are plenty of publications, and now a study by the NIA/NIH (at the ICAD 2008)that has proven the TNF inhibitor theory to be valid against Alzheimer's. Many of us who have had to deal with Ger on other blogs believe his biased copy and paste comments are for his own gain, from a competing pharmaceutical company, namely Elan. My reason for the posts is so that my Mom can keep receiving the treatments, which since we've started have helped her maintain for 7 months now...even through major surgery (colectomy) this last July. Please don't help Ger stop people from believing...it's too important for us caregivers.

Felicia
famc17 (at) yahoo.com

9. globalstay on September 28, 2008 1:22 AM writes...

german boat all sun me trust vacant yahoo

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