Corante

About this Author
DBL%20Hendrix%20small.png College chemistry, 1983

Derek Lowe The 2002 Model

Dbl%20new%20portrait%20B%26W.png After 10 years of blogging. . .

Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: derekb.lowe@gmail.com Twitter: Dereklowe

Chemistry and Drug Data: Drugbank
Emolecules
ChemSpider
Chempedia Lab
Synthetic Pages
Organic Chemistry Portal
PubChem
Not Voodoo
DailyMed
Druglib
Clinicaltrials.gov

Chemistry and Pharma Blogs:
Org Prep Daily
The Haystack
Kilomentor
A New Merck, Reviewed
Liberal Arts Chemistry
Electron Pusher
All Things Metathesis
C&E News Blogs
Chemiotics II
Chemical Space
Noel O'Blog
In Vivo Blog
Terra Sigilatta
BBSRC/Douglas Kell
ChemBark
Realizations in Biostatistics
Chemjobber
Pharmalot
ChemSpider Blog
Pharmagossip
Med-Chemist
Organic Chem - Education & Industry
Pharma Strategy Blog
No Name No Slogan
Practical Fragments
SimBioSys
The Curious Wavefunction
Natural Product Man
Fragment Literature
Chemistry World Blog
Synthetic Nature
Chemistry Blog
Synthesizing Ideas
Business|Bytes|Genes|Molecules
Eye on FDA
Chemical Forums
Depth-First
Symyx Blog
Sceptical Chymist
Lamentations on Chemistry
Computational Organic Chemistry
Mining Drugs
Henry Rzepa


Science Blogs and News:
Bad Science
The Loom
Uncertain Principles
Fierce Biotech
Blogs for Industry
Omics! Omics!
Young Female Scientist
Notional Slurry
Nobel Intent
SciTech Daily
Science Blog
FuturePundit
Aetiology
Gene Expression (I)
Gene Expression (II)
Sciencebase
Pharyngula
Adventures in Ethics and Science
Transterrestrial Musings
Slashdot Science
Cosmic Variance
Biology News Net


Medical Blogs
DB's Medical Rants
Science-Based Medicine
GruntDoc
Respectful Insolence
Diabetes Mine


Economics and Business
Marginal Revolution
The Volokh Conspiracy
Knowledge Problem


Politics / Current Events
Virginia Postrel
Instapundit
Belmont Club
Mickey Kaus


Belles Lettres
Uncouth Reflections
Arts and Letters Daily
In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

In the Pipeline

« Things I'm Glad I Don't Do: Isolating Ciguatoxin | Main | Full Disclosure »

May 3, 2006

Have The Rules Changed?

Email This Entry

Posted by Derek

I'll address this more in tomorrow's post, but everyone should know that there was a potentially very interesting ruling yesterday by the DC Circuit Court of Appeals. Do patients have a right to drugs after Phase I? We might be heading back to the days before efficacy testing was required. . .read this post at Marginal Revolution to get up to speed.

I've spoken about this issue a bit before. Back in 2002 I was very doubtful about the whole idea, but my opinion has been slowly changing. I didn't expect that this is how things would change, but you should never underestimate the courts. More anon.

Comments (2) + TrackBacks (0) | Category: Drug Development


COMMENTS

1. Dr Toot on May 3, 2006 3:05 PM writes...

If I glanced at my FierceTech blurb correctly, & that is never a given, I had thought that this issue was in reference to allowing post-Phase 1 drugs to be given to terminally ill persons, provided there was some reasonable chance they might help.

In my opinion, such persons should be given a government-funded option to die in dignity, in a manner of their own choosing. Arguing over allowing them access to Phase 1 drugs is somewhat akin to arguing that Jews should not be forced to wear armbands while on their way to the ovens.

Quite frankly, the dialectic here allows for a sublime example of the difference between those who are truly compassionate, & those who wish to be seen as such and/or convince themselves that they are.

Of course, maybe you're talking about something else, in which case f*ck me.

Permalink to Comment

2. AMedChemist on May 4, 2006 4:17 PM writes...

Hey Derek,

They referenced your blog in Forbes:

"Patenting big swaths of important biochemical pathway space has the potential to turn drug development into even more of an expensive nightmare than it already is," pharmaceutical chemist Derek Lowe wrote in his blog, In The Pipeline, last month. Lowe, who works for a major pharmaceutical firm, was writing specifically about the Ariad case. Since making that statement, Lowe had posted that he had shorted Ariad's stock ahead of the ruling."

Nice!

Permalink to Comment

POST A COMMENT




Remember Me?



EMAIL THIS ENTRY TO A FRIEND

Email this entry to:

Your email address:

Message (optional):




RELATED ENTRIES
Gitcher SF5 Groups Right Here
Changing A Broken Science System
One and Done
The Latest Protein-Protein Compounds
Professor Fukuyama's Solvent Peaks
Novartis Gets Out of RNAi
Total Synthesis in Flow
Sweet Reason Lands On Its Face