About this Author
DBL%20Hendrix%20small.png College chemistry, 1983

Derek Lowe The 2002 Model

Dbl%20new%20portrait%20B%26W.png After 10 years of blogging. . .

Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: Twitter: Dereklowe

Chemistry and Drug Data: Drugbank
Chempedia Lab
Synthetic Pages
Organic Chemistry Portal
Not Voodoo

Chemistry and Pharma Blogs:
Org Prep Daily
The Haystack
A New Merck, Reviewed
Liberal Arts Chemistry
Electron Pusher
All Things Metathesis
C&E News Blogs
Chemiotics II
Chemical Space
Noel O'Blog
In Vivo Blog
Terra Sigilatta
BBSRC/Douglas Kell
Realizations in Biostatistics
ChemSpider Blog
Organic Chem - Education & Industry
Pharma Strategy Blog
No Name No Slogan
Practical Fragments
The Curious Wavefunction
Natural Product Man
Fragment Literature
Chemistry World Blog
Synthetic Nature
Chemistry Blog
Synthesizing Ideas
Eye on FDA
Chemical Forums
Symyx Blog
Sceptical Chymist
Lamentations on Chemistry
Computational Organic Chemistry
Mining Drugs
Henry Rzepa

Science Blogs and News:
Bad Science
The Loom
Uncertain Principles
Fierce Biotech
Blogs for Industry
Omics! Omics!
Young Female Scientist
Notional Slurry
Nobel Intent
SciTech Daily
Science Blog
Gene Expression (I)
Gene Expression (II)
Adventures in Ethics and Science
Transterrestrial Musings
Slashdot Science
Cosmic Variance
Biology News Net

Medical Blogs
DB's Medical Rants
Science-Based Medicine
Respectful Insolence
Diabetes Mine

Economics and Business
Marginal Revolution
The Volokh Conspiracy
Knowledge Problem

Politics / Current Events
Virginia Postrel
Belmont Club
Mickey Kaus

Belles Lettres
Uncouth Reflections
Arts and Letters Daily
In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

In the Pipeline

« A Technical Question | Main | Maybe They Should Fire Them All? »

February 7, 2005

One Problem Solved, Anyway

Email This Entry

Posted by Derek

Before I start off tonight, I wanted to welcome another advertiser on the site, the folks at GenomeWeb over there in the corner. Glad to have 'em!

Thanks to the people who commented on yesterday's question. My Corantean overlord(s) suggested a useful solution as well, since (as Jack Vinson guessed), I'm set up to only display the most recent posts on the front page. Pasting in the old material, saving it as a draft, and then changing its date sends it directly to the category without having it appear up front.

So, the first thing I've added from the archives is my series on chemical warfare, which was written in September of 2002. It's in that "Chem/Bio Warfare" category over on the right, naturally enough. (This was written in the run-up to the Iraq war, and the last post in the series was soon overtaken by events. I note, though, that I speculated that Iraq might have far less in its stockpiles than people had estimated - I just didn't realize quite how much less.) But most of the series is still worth a read, if you're interested in that sort of thing. You'll learn about the morning that a German chemist first synthesized a human nerve gas, not realizing quite what he'd made until it was time to dive for the door. And you'll hear about my own cold-sweat encounter with phosgene gas, which I hope not to repeat any time soon.

This'll be it for tonight. I'll be heading into the lab tomorrow morning to see if I have a useful one-pot way to make a five-membered heterocycle, or if I have an orange mess in the bottom of my flask. The most likely outcome is that it won't work, and if it works, the most likely result is two different isomers (with the wrong one predominating.) But I don't know any of that for sure, and that's why we run the darn experiments, y'know. Hope springs eternal - that's one thing we prove in research every morning.

Comments (1) + TrackBacks (0) | Category: Blog Housekeeping


1. jsinger on February 9, 2005 9:49 AM writes...

The GenomeWeb daily email service is very worth signing up for...

Permalink to Comment


Email this entry to:

Your email address:

Message (optional):

The Last Post
The GSK Layoffs Continue, By Proxy
The Move is Nigh
Another Alzheimer's IPO
Cutbacks at C&E News
Sanofi Pays to Get Back Into Oncology
An Irresponsible Statement About Curing Cancer
Oliver Sacks on Turning Back to Chemistry