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DBL%20Hendrix%20small.png College chemistry, 1983

Derek Lowe The 2002 Model

Dbl%20new%20portrait%20B%26W.png After 10 years of blogging. . .

Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. He's worked for several major pharmaceutical companies since 1989 on drug discovery projects against schizophrenia, Alzheimer's, diabetes, osteoporosis and other diseases. To contact Derek email him directly: derekb.lowe@gmail.com Twitter: Dereklowe

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In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

In the Pipeline

« Let's See What the Sharks Think of These Steaks! | Main | A Visit To Academia »

November 3, 2004

Don't Ask; Just Trade

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Posted by Derek

At the risk of perpetuating the idea that my support of Bush was purely economic, it's worth noting that his re-election had an immediate impact on the pharmaceutical stocks.

The exception was the stock of companies closely identified with stem cell research. I should have gone short, darn it all. You have three reasonably pure plays in that category: Geron, Stemcells, and Aastrom, and they all got gonged today. (Likewise, they'd all been rising as the possibility of a Kerry win increased.)

And that's fairly silly. The Bush administration's stem cell policy (which I oppose), is to restrict public funding for research in the area. With private money, you can do what you want to do, and guess what? The biotech industry is the very definition of "private money." You could argue that the restrictions on NIH funding hold back the whole field (which is surely the case), making it less likely that commercial applications will be coming soon. But perhaps taking academia partly out of the game increases the chance that a major discovery would be completely owned by a company, rather than in-licensed.

At any rate, it's not like all three companies are focused on embryonic stem cell research. They just trade as if they were. Aastrom stock, for example, has been jerked around for years by clueless traders who don't bother to read the company's own press releases, which clearly state that they use only adult-derived stem cells. You know, the kind with no research restrictions on them? Ah, the efficient market.

Comments (2) + TrackBacks (0) | Category: Business and Markets


COMMENTS

1. jeet on November 4, 2004 2:34 PM writes...

true, but there aren't many scientist working on these therapies in the academic ranks right now (maybe due to lack of funding) and biotech start-ups depend a great deal on the transfer of not-quite ready technologies and people that have been working on them from the academic sector.



kind of goes back to one of the reasons why boston and san diego are areas where pharma is putting up research sites. they have an industry focus, a supply of talent, a supply of start-ups and a supply of capital.



in my opinion there is a gap in stem cell research (embryonic or not) when compared to the typical model of how bio-technologies move from conceptual to market.



the bigger worry is that Japanese and UK companies (where government investment is heavy) will be the ones developing a lion's share of IP and early clinical candidates. if they do that we will still pay for these therapies but the profits will be going to companies overseas.

Permalink to Comment

2. John on November 5, 2004 3:37 PM writes...

I wouldn't worry about Japan. There are no really true biotechs over there, and most of the non-Big J-Pharma Company research is done by food companies with delusions of becoming players in Pharma (Kirin, Suntory, Japan Tobacco, etc.). The sclerotic management and poor clinical infrastructure in Japan will be a big impdiment to progress. Chugai might make some progress from their biologicals programs, but Roche is going to reap the benefit (and probably spring for a lot of the development, too).

Only economists think markets are purely efficient. Us marketers know different: economics is the science of equilibria, marketing is the science of disequilibria. Can you guess where most money is made?

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